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1. General Infomation:

Shandong ProvincialKey Laboratory of Oral Tissue Regeneration is one of the key laboratories in Shandong University. It has been put into use since 2003 andhas been relocated to Jinan Pharmaceutical Valleysince 2016.

The laboratory covers an area of 3200 square meters. It has six main functional experimental platforms, including molecular biology, cell biology, microbiology, histomorphology, animal center and precision equipment.

The total cost of laboratory equipment is about 12 million Yuan.The lab possesses 8 pieces of large equipmentwhich costmore than 100,000 Yuan. Other precious instruments include two Roche real-time quantitative PCR instruments, hard tissue cutting system, BD flow cytometer, GE multicolor fluorescence imager, Millipore ultrapure water system, DG250 anaerobic workstation, and large mouse IVC feeding system. The staffs regularly conduct technical training and examination to ensure everything work well.

The laboratory implements the PI responsible system. It has astudio for Fu Xiaobing, who is a famous academician of China. There are 38 regular scientific researchers, including one top-notch youngscholar in the National "Ten Thousands Plan", three people who enjoy special allowances from the State Council, one specialist of Taishan scholars of Shandong Province and so on. We have 18 professors, 2 researchers, 2 chief physicians, 14 associate professors and 2 deputy chief physicians. The laboratory formed an academic committee headed byProfessorZhiyuan Zhan, an academician of the Chinese Academy of Engineering.

The laboratory implements the rule of “open, competitive and dynamic operation” and sets up "OpenResearch Projects" to deepen scientific research almost every year.

2. Main Research Fields and professors:

(1) Basic research and clinical transformation of oral tissue engineering technology.

Principal Investigator:Xin Xu.

Fellows:Professor Pishan Yang, Professor Shaohua Ge, Professor Fulang We, Associate Professor Yong Wen.

(2) Host factors research and safety evaluation of oral tissue engineering.

Principal Investigator: Fenghe Zhang.

Fellows:Professor Hui Song, Professor Shu Li, Associate Professor Jin Zhang, Associate Professor Shiguo Yan.

(3) Mechanism research of hard tissue occurrence and related diseases

Principal Investigator:Minqi Li.

Fellows:Professor Jie Guo, Associate Professor Fan Zhang, Associate Professor Haiyun Huang, Associate Professor Di Liu.

(4) Skin tissue engineering

Principal Investigator:Xunwei Wu.

Fellows:two post-doctors, one doctoral student, three technicians.

(5) Oral micro-ecology.

Principal Investigator: Qiang Feng.

(6) Research and development of oral materials.

Principal Investigator: Jianhua Li

3. Staff:

(1) Pishan Yang, Professor, Director ofOral Tissue Regeneration Laboratory

(2) Shu Li, Professor, Vice Director ofOral Tissue Regeneration Laboratory

(3) Zhennan Gao, Associate Professor ofOral Tissue Regeneration Laboratory

(4) Qian xu, Technician ofOral Tissue Regeneration Laboratory

(5) Shuang Liu, Technician ofOral Tissue Regeneration Laboratory

(6) Xiaojing Liu, Technician ofOral Tissue Regeneration Laboratory

(7) Linghong Liu, Technician ofOral Tissue Regeneration Laboratory

(8) Manrui Zhang,management staff ofOral Tissue Regeneration Laboratory

(9) Jing Guo,management staff ofOral Tissue Regeneration Laboratory

(10) Hong An,management staff ofOral Tissue Regeneration Laboratory